At the Mediterranean Basin, lemons have found remarkable cultural and commercial interest: Sicilia represents the most important lemon production site of the Mediterranean. The origin of the “Femminello” lemon is unknown. It is likely to be one of the first kinds of lemons introduced in Sicilia, given that “Femminello” can be found all around the island. The fruit is changeable when it comes to size, shape, thickness of the peel, number of seeds and percentage and composition of the juice. The plant is vigorous with a big and lengthened fruit, the juice abundant and perfumed, slightly sour. The common Femminello is the most spread and priced variety by the abundant production and the resistant to manipulation and transportation.